Institute of Pharmaceutical Sciences, SAGE University, Indore (M.P.)
Fast dissolving films (FDFs) have become a promising and innovative drug delivery system. These systems offer a prominent alternative to conventional dosage forms as it disintegrates and dissolves rapidly in saliva without the need of water and swallowing making them particularly advantageous for pediatric, geriatric, and dysphagic patients who experience difficulty in swallowing conventional oral dosage forms. The increasing demand for rapid drug delivery and patient-friendly dosage form has given rise to the extensive research in the development of FDFs. This review provides an in- depth overview of the Fast dissolving films along with their advantages, disadvantages, ormulation strategies, key components, manufacturing technologies involved in their development and their evaluation parameters Furthermore, this review also discusses about the selection of suitable film-forming polymers, plasticizers, sweeteners, and active pharmaceutical ingredients and other excipients which are important for achieving the desired mechanical properties, rapid disintegration, and drug release profiles.
